β1 Syntrophin Supports Autophagy Initiation and Protects against Cerulein-Induced Acute Pancreatitis

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Protective Effects of Lithospermum erythrorhizon Against Cerulein-Induced Acute Pancreatitis

OBJECTIVES We aimed to evaluate the anti-inflammatory and inhibitory effects of Lithospermum erythrorhizon (LE) on cerulein-induced acute pancreatitis (AP) in a mouse model. METHODS Acute pancreatitis was induced via intraperitoneal injection of cerulein (50 μg/kg) every hour for 6 times. In the LE, water extract (100, 250, or 500 mg/kg) was administered intraperitoneally 1 hour before the fi...

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Protective effects of Curcuma longa against cerulein-induced acute pancreatitis and pancreatitis-associated lung injury.

Curcuma longa (CL) has been reported to possess a variety of pharmacological activities. However, the effects of CL on acute pancreatitis (AP) have not yet been determined. To this end, we examined the effects of CL on cerulein-induced AP. Cell viability and cytokine productions were measured in pancreatic acini. Mice were divided into 3 groups: i) Normal group, ii) normal saline-treated group,...

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Heat Shock Proteins and Autophagy in Rats with Cerulein-Induced Acute Pancreatitis

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ژورنال

عنوان ژورنال: The American Journal of Pathology

سال: 2019

ISSN: 0002-9440

DOI: 10.1016/j.ajpath.2019.01.002